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To ask His Majesty's Government whether the forthcoming mental health strategy for England will address the safety of medicines with psychiatric risk profiles when prescribed for physical health indications; and how the strategy's alignment with the suicide prevention strategy for England will reflect the findings of the Health Services Safety...
To ask His Majesty's Government whether the forthcoming mental health strategy for England will address the safety of medicines with psychiatric risk profiles when prescribed for physical health indications; and how the strategy's alignment with the suicide prevention strategy for England will reflect the findings of the Health Services Safety...
The Government is developing a new cross-Government mental health strategy for England, to be published later this year. The detailed content of the mental health strategy is still being developed.
To ask the Secretary of State for Health and Social Care, how many of the suspected adverse reaction reports of unknown age for the COVID-19 Vaccine Moderna monovalent were followed up by the Medicines and Healthcare products Regulatory Agency to try and recover the missing information.
To ask the Secretary of State for Health and Social Care, how many of the suspected adverse reaction reports of unknown age for the COVID-19 Vaccine Moderna monovalent were followed up by the Medicines and Healthcare products Regulatory Agency to try and recover the missing information.
To ask His Majesty's Government what assessment they have made of the findings of an inquest at Norfolk Coroner's Court that a death by suicide was the result of side effects of finasteride; and whether they intend to commission further research on the implications for public policy and public safety.
To ask His Majesty's Government what assessment they have made of the findings of an inquest at Norfolk Coroner's Court that a death by suicide was the result of side effects of finasteride; and whether they intend to commission further research on the implications for public policy and public safety.
The Medicines and Healthcare products Regulatory Agency (MHRA) fully reviews and responds to all Prevention of Future Death report actions where they fall under the remit of the agency. The MHRA has not raised any report from Norfolk Coroner’s Court with the Department concerning the side effects of finasteride.
In 2024, the MHRA completed a thorough safety review into finasteride following concerns raised regarding a potential lack of awareness of its side effects amongst patients and healthcare professionals. I have attached a copy of the detailed public assessment report prepared by the MHRA following this safety review.
The MHRA has also published various drug safety updates to raise awareness of the risks of psychiatric side effects and sexual dysfunction associated with finasteride, including the risk of depression and suicidal thoughts. Patients are advised to stop using finasteride immediately if they develop depression or suicidal thoughts and seek advice from their healthcare professional, if any of the listed side effects become serious, or if they experience any side effects not listed in the patient information leaflet. Patient alert cards are being introduced in all finasteride packs to reiterate these warnings.
Patient safety is the MHRA’s top priority and it will continue to monitor finasteride and take any regulatory action required, based on any substantial new evidence that emerges.
To ask His Majesty's Government what discussions they have had with the Medicines and Healthcare products Regulatory Agency regarding the findings of an inquest at Norfolk Coroner's Court that a death by suicide was the result of side effects of finasteride; and what plans they have to commission further research on...
To ask His Majesty's Government what discussions they have had with the Medicines and Healthcare products Regulatory Agency regarding the findings of an inquest at Norfolk Coroner's Court that a death by suicide was the result of side effects of finasteride; and what plans they have to commission further research on...
The Medicines and Healthcare products Regulatory Agency (MHRA) fully reviews and responds to all Prevention of Future Death report actions where they fall under the remit of the agency. The MHRA has not raised any report from Norfolk Coroner’s Court with the Department concerning the side effects of finasteride.
In 2024, the MHRA completed a thorough safety review into finasteride following concerns raised regarding a potential lack of awareness of its side effects amongst patients and healthcare professionals. I have attached a copy of the detailed public assessment report prepared by the MHRA following this safety review.
The MHRA has also published various drug safety updates to raise awareness of the risks of psychiatric side effects and sexual dysfunction associated with finasteride, including the risk of depression and suicidal thoughts. Patients are advised to stop using finasteride immediately if they develop depression or suicidal thoughts and seek advice from their healthcare professional, if any of the listed side effects become serious, or if they experience any side effects not listed in the patient information leaflet. Patient alert cards are being introduced in all finasteride packs to reiterate these warnings.
Patient safety is the MHRA’s top priority and it will continue to monitor finasteride and take any regulatory action required, based on any substantial new evidence that emerges.
To ask the Secretary of State for Health and Social Care, what steps he is taking to provide acknowledgement and redress to people who had faces damaged and developed serious side effects after retraction-extraction orthodontics during childhood.
To ask the Secretary of State for Health and Social Care, what steps he is taking to provide acknowledgement and redress to people who had faces damaged and developed serious side effects after retraction-extraction orthodontics during childhood.
The Department is unable to intervene in or comment on individual cases. However, information for patients who have concerns or complaints about the treatments they have received on how to raise those issues with the relevant bodies is available at the following links:
https://www.england.nhs.uk/contact-us/feedback-and-complaints/complaint/
https://www.gdc-uk.org/raising-concerns/how-to-get-a-refund-or-make-a-complaint
According to orthodontic experts, dental extractions are undertaken to provide space when it is felt that attempting to correct a malocclusion would lead to harm. This is either to address crowding or correct anteroposterior, lateral, or vertical mal-relationships of the teeth or jaws. A recent systematic review published in the European Journal of Orthodontics suggests that extraction of premolars in orthodontic treatment does not negatively affect upper airway volume and minimum cross-sectional area. The review is available at the following link:
Lords motion to approve. Amendment to regret debated and withdrawn. Original motion agreed to on question.
Lords motion to approve. Amendment to regret debated and withdrawn. Original motion agreed to on question.
My Lords, we must never lose sight of why we are here to debate these regulations. The infected blood scandal was a catastrophic failure of the state. It is a tragedy measured not only by the pain and suffering of its victims but by the decades it took for the...
My Lords, we must never lose sight of why we are here to debate these regulations. The infected blood scandal was a catastrophic failure of the state. It is a tragedy measured not only by the pain and suffering of its victims but by the decades it took for the...
Moved by
Baroness Brinton
Moved by
Baroness Brinton
My Lords, time is short not just for speakers in this debate, but increasingly so for the remaining victims of infected blood to get justice after one of the biggest ever failures by the British state on record. Curiously enough, all infected blood records are missing in Northern Ireland, for...
My Lords, time is short not just for speakers in this debate, but increasingly so for the remaining victims of infected blood to get justice after one of the biggest ever failures by the British state on record. Curiously enough, all infected blood records are missing in Northern Ireland, for...
My Lords, we must thank the noble Baroness, Lady Brinton, for her introduction to this amendment. Like others, I have had some desperately sad correspondence from widows whose husbands died relatively early after infection. Infection denied them children, some suffered serious discrimination within their family, some find that their husbands...
My Lords, we must thank the noble Baroness, Lady Brinton, for her introduction to this amendment. Like others, I have had some desperately sad correspondence from widows whose husbands died relatively early after infection. Infection denied them children, some suffered serious discrimination within their family, some find that their husbands...
My Lords, it is a great pleasure to follow the noble Baroness, Lady Finlay, and all the speakers in this debate thus far. I continue where she left off, taking a moment to look at the big picture.
We have a huge problem with trust in politics and government in our...
My Lords, it is a great pleasure to follow the noble Baroness, Lady Finlay, and all the speakers in this debate thus far. I continue where she left off, taking a moment to look at the big picture.
We have a huge problem with trust in politics and government in our...
My Lords, my mum Sheila Davies died from liver cancer in 2017 after a long battle with hepatitis. She did not drink, she never smoked, and I think she went out of the country a grand total of three times. In fact, she rarely ventured outside Plymouth, where she worked...
My Lords, my mum Sheila Davies died from liver cancer in 2017 after a long battle with hepatitis. She did not drink, she never smoked, and I think she went out of the country a grand total of three times. In fact, she rarely ventured outside Plymouth, where she worked...
My Lords, it is an honour to follow the noble Baroness. When one hears stories directly like that, they have an impact. I am so sorry for the noble Baroness’s loss. As ever, I have to declare my interest: one of my sister’s twin boys—my nephew, who was a haemophiliac—was...
My Lords, it is an honour to follow the noble Baroness. When one hears stories directly like that, they have an impact. I am so sorry for the noble Baroness’s loss. As ever, I have to declare my interest: one of my sister’s twin boys—my nephew, who was a haemophiliac—was...
My Lords, it is a pleasure to follow the noble Baroness. I want to mention in particular the contribution from the noble Baroness, Lady Davies of Devonport, who set out so powerfully the real-world consequences of this scandal: not just the infections but the stigma that went with them. I...
My Lords, it is a pleasure to follow the noble Baroness. I want to mention in particular the contribution from the noble Baroness, Lady Davies of Devonport, who set out so powerfully the real-world consequences of this scandal: not just the infections but the stigma that went with them. I...
I am deeply conscious of how much knowledge many noble Lords have on this topic, knowledge that has often been tragically accumulated through their own personal experiences and those of their families. I pay tribute to those, both in this House and outside it, who have done so much to...
I am deeply conscious of how much knowledge many noble Lords have on this topic, knowledge that has often been tragically accumulated through their own personal experiences and those of their families. I pay tribute to those, both in this House and outside it, who have done so much to...
My Lords, before I speak to the Motion to approve these regulations and to the regret amendment in the name of the noble Baroness, Lady Brinton, I want to begin by reflecting on the courage and tenacity of all infected and affected victims of the infected blood scandal. They have...
My Lords, before I speak to the Motion to approve these regulations and to the regret amendment in the name of the noble Baroness, Lady Brinton, I want to begin by reflecting on the courage and tenacity of all infected and affected victims of the infected blood scandal. They have...
My Lords, before I start, I put on record that I am in awe of the noble Baroness, Lady Davies, and her speech. I can only imagine how difficult it was for her to stand up and do that. She demonstrates what we have all listened to on many occasions:...
My Lords, before I start, I put on record that I am in awe of the noble Baroness, Lady Davies, and her speech. I can only imagine how difficult it was for her to stand up and do that. She demonstrates what we have all listened to on many occasions:...
I thank the Minister for her introduction to the SI and for the recent meeting. I will ask her many questions. If she cannot answer them all, I will look forward to hearing from her in due course. I have tabled this amendment because of very serious disquiet from infected...
I thank the Minister for her introduction to the SI and for the recent meeting. I will ask her many questions. If she cannot answer them all, I will look forward to hearing from her in due course. I have tabled this amendment because of very serious disquiet from infected...
My Lords, I thank the noble Baroness, Lady Davies of Devonport, for her very moving contribution about her mother’s own experience, reminding us of the consequences of stigma, hidden infections and diseases such as hepatitis not being identified, which meant that she could not be treated. I understand what it...
My Lords, I thank the noble Baroness, Lady Davies of Devonport, for her very moving contribution about her mother’s own experience, reminding us of the consequences of stigma, hidden infections and diseases such as hepatitis not being identified, which meant that she could not be treated. I understand what it...
To ask the Secretary of State for Health and Social Care, whether the Yellow Card adverse drug reaction reference GB-MHRA-MED-202605220730230940-NSQYR (linked to case file CEC 256289) is being actively reviewed by the clinical assessors of the Neurology, Pain and Psychiatry Expert Advisory Group as part of their current, ongoing safety...
To ask the Secretary of State for Health and Social Care, whether the Yellow Card adverse drug reaction reference GB-MHRA-MED-202605220730230940-NSQYR (linked to case file CEC 256289) is being actively reviewed by the clinical assessors of the Neurology, Pain and Psychiatry Expert Advisory Group as part of their current, ongoing safety...
The Medicines and Healthcare products Regulatory Agency (MHRA) confirms that in June 2026, the Neurology, Pain and Psychiatry Expert Advisory Group (NPPEAG) considered an assessment of clozapine drug level monitoring. The NPPEAG provided advice about the requirements for this type of monitoring. At present, clozapine drug-level monitoring is required only in specific clinical situations, partly because of the high level of variability between patients. The MHRA is taking forward the NPPEAG’s recommendations and will communicate to healthcare professionals once the regulatory position is finalised.
The review of clozapine drug-level monitoring focused on clinical and scientific data to establish the value of this type of monitoring in clinical practice. It took into account a range of information, including overall reporting patterns and themes in reports received through the Yellow Card scheme, but did not include clinical review of individual Yellow Card reports. MHRA safety assessments may also consider the views of patients and other stakeholders.
The MHRA will be launching a survey in the summer to gather information on awareness of key risks associated with clozapine, and to assess whether additional measures would be helpful for patients, their families, and carers, as well as healthcare professionals involved in the care of patients receiving clozapine.